Tuesday, January 28, 2020

The Concept of Probability in Mathematics

The Concept of Probability in Mathematics Probability is a way of expressing knowledge or belief that an event will occur or has occurred. The concept has been given an exact mathematical meaning in probability theory, which is used extensively in such areas of study as mathematics, statistics, finance, gambling, science, and philosophy to draw conclusions about the likelihood of potential events and the underlying mechanics of complex systems. The word probability does not have a consistent direct definition. In fact, there are two broad categories of probability interpretations, whose adherents possess different views about the fundamental nature of probability. The word Probability derives from Latin word probabilitas that can also mean probity, a measure of the authority of a witness in a legal case in Europe, and often correlated with the witnesss nobility. In a sense, this differs much from the modern meaning of probability, which, in contrast, is used as a measure of the weight of empirical evidence, and is arrived at from inductive reasoning and statistical inference. History: The scientific study of probability is a modern development. Gambling shows that there has been an interest in quantifying the ideas of probability for millennia, but exact mathematical descriptions of use in those problems only arose much later. According to Richard Jeffrey, Before the middle of the seventeenth century, the term probable meant approvable, and was applied in that sense, univocally, to opinion and to action. A probable action or opinion was one such as sensible people would undertake or hold, in the circumstances.[4] However, in legal contexts especially, probable could also apply to propositions for which there was good evidence. Aside from some elementary considerations made by Girolamo Cardano in the 16th century, the doctrine of probabilities dates to the correspondence of Pierre de Fermat and Blaise Pascal (1654). Christiaan Huygens (1657) gave the earliest known scientific treatment of the subject. Jakob Bernoullis and Abraham de Moivres Doctrine of Chances (1718) treated the subject as a branch of mathematics. See Ian Hackings The Emergence of Probability and James Franklins The Science of Conjecture for histories of the early development of the very concept of mathematical probability. The theory of errors may be traced back to Roger Cotes but a memoir prepared by Thomas Simpson in 1755 (printed 1756) first applied the theory to the discussion of errors of observation. The reprint (1757) of this memoir lays down the axioms that positive and negative errors are equally probable, and that there are certain assignable limits within which all errors may be supposed to fall; continuous errors are discussed and a probability curve is given. Pierre-Simon Laplace (1774) made the first attempt to deduce a rule for the combination of observations from the principles of the theory of probabilities. He represented the law of probability of errors by a curve y = à Ã¢â‚¬  (x), x being any error and y its probability.He also gave (1781) a formula for the law of facility of error (a term due to Lagrange, 1774), but one which led to unmanageable equations. Daniel Bernoulli (1778) introduced the principle of the maximum product of the probabilities of a system of concurrent errors. The method of least squares is due to Adrien-Marie Legendre (1805), who introduced it in his New Methods for Determining the Orbits of Comets. In ignorance of Legendres contribution, an Irish-American writer, Robert Adrain, editor of The Analyst (1808), first deduced the law of facility of error, h being a constant depending on precision of observation, and c a scale factor ensuring that the area under the curve equals 1. He gave two proofs, the second being essentially the same as John Herschels (1850). Gauss gave the first proof which seems to have been known in Europe (the third after Adrains) in 1809. Further proofs were given by Laplace (1810, 1812), Gauss (1823), James Ivory (1825, 1826), Hagen (1837), Friedrich Bessel (1838), W. F. Donkin (1844, 1856), and Morgan Crofton (1870). Other contributors were Ellis (1844), De Morgan (1864), Glaisher (1872), and Giovanni Schiaparelli (1875). Peterss (1856) formula for r, the probable error of a single observation, is well known. In the nineteenth century authors on the general theory included Laplace, Sylvestre Lacroix (1816), Littrow (1833), Adolphe Quetelet (1853), Richard Dedekind (1860), Helmert (1872), Hermann Laurent (1873), Liagre, Didion, and Karl Pearson. Augustus De Morgan and George Boole improved the exposition of the theory. Andrey Markov introduced the notion of Markov chains (1906) playing an important role in theory of stochastic processes and its applications. The modern theory of probability based on the measure theory was developed by Andrey Kolmogorov (1931). On the geometric side, contributors to The Educational Times were influential. Types of probability: There are basically four types of probabilities, each with its limitations. None of these approaches to probability is wrong, but some are more useful or more general than others. Classical Probability: The classical interpretation owes its name to its early and august pedigree. Championed by Laplace, and found even in the works of Pascal, Bernoulli, Huygens, and Leibniz, it assigns probabilities in the absence of any evidence, or in the presence of symmetrically balanced evidence. The classical theory of probability applies to equally probable events, such as the outcomes of tossing a coin or throwing dice; such events were known as equipossible. probability = number of favourable equipossibilies / total number of relevant equipossibilities. Logical probability: Logical theories of probability retain the classical interpretations idea that probabilities can be determined a priori by an examination of the space of possibilities. Subjective probability: A probability derived from an individuals personal judgment about whether a specific outcome is likely to occur. Subjective probabilities contain no formal calculations and only reflect the subjects opinions and past experience. Subjective probabilities differ from person to person. Because the probability is subjective, it contains a high degree of personal bias. An example of subjective probability could be asking New York Yankees fans, before the baseball season starts, the chances of New York winning the world series. While there is no absolute mathematical proof behind the answer to the example, fans might still reply in actual percentage terms, such as the Yankees having a 25% chance of winning the world series. In everyday speech, we express our beliefs about likelihoods of events using the same terminology as in probability theory. Often, this has nothing to do with any formal definition of probability, rather it is an intuitive idea guided by our experience, and in some cases statistics. Some Of the Examples Of Probability: X says Dont buy the avocados here; about half the time, theyre rotten. X is expressing his belief about the probability of an event that an avocado will be rotten based on his personal experience. Y says I am 95% certain the capital of Spain is Barcelona. Here, the belief Y is expressing is only a probability from his point of view, because only he does not know that the capital of Spain is Madrid (from our point of view, the probability is 100%). However, we can still view this as a subjective probability because it expresses a measure of uncertainty. It is as though Y is saying in 95% of cases where I feel as sure as I do about this, I turn out to be right. Z says There is a lower chance of being shot in Omaha than in Detroit. Z is expressing a belief based (presumably) on statistics. Dr. A says to Christina, There is a 75% chance that you will live. Dr. A is basing this off of his research. Probability can also be expressed in vague terms. For example, someone might say it will probably rain tomorrow. This is subjective, but implies that the speaker believes the probability is greater than 50%. Subjective probabilities have been extensively studied, especially with regards to gambling and securities markets. While this type of probability is important, it is not the subject of this book. There are two standard approaches to conceptually interpreting probabilities. The first is known as the long run (or the relative frequency approach) and the subjective belief (or confidence approach). In the Frequency Theory of Probability, probability is the limit of the relative frequency with which an event occurs in repeated trials (note that trials must be independent). Frequentists talk about probabilities only when dealing with experiments that are random and well-defined. The probability of a random event denotes the relative frequency of occurrence of an experiments outcome, when repeating the experiment. Frequentists consider probability to be the relative frequency in the long run of outcomes. Physical probabilities, which are also called objective or frequency probabilities, are associated with random physical systems such as roulette wheels, rolling dice and radioactive atoms. In such systems, a given type of event (such as the dice yielding a six) tends to occur at a persistent rate, or relative frequency, in a long run of trials. Physical probabilities either explain, or are invoked to explain, these stable frequencies. Thus talk about physical probability makes sense only when dealing with well defined random experiments. The two main kinds of theory of physical probability are frequentist accounts and propensity accounts. Relative frequencies are always between 0% (the event essentially never happens) and 100% (the event essentially always happens), so in this theory as well, probabilities are between 0% and 100%. According to the Frequency Theory of Probability, what it means to say that the probability that A occurs is p% is that if you repeat the experiment over and over again, independently and under essentially identical conditions, the percentage of the time that A occurs will converge to p. For example, under the Frequency Theory, to say that the chance that a coin lands heads is 50% means that if you toss the coin over and over again, independently, the ratio of the number of times the coin lands heads to the total number of tosses approaches a limiting value of 50% as the number of tosses grows. Because the ratio of heads to tosses is always between 0% and 100%, when the probability exists it must be between 0% and 100%. In the Subjective Theory of Probability, probability measures the speakers degree of belief that the event will occur, on a scale of 0% (complete disbelief that the event will happen) to 100% (certainty that the event will happen). According to the Subjective Theory, what it means for me to say that the probability that A occurs is 2/3 is that I believe that A will happen twice as strongly as I believe that A will not happen. The Subjective Theory is particularly useful in assigning meaning to the probability of events that in principle can occur only once. For example, how might one assign meaning to a statement like there is a 25% chance of an earthquake on the San Andreas fault with magnitude 8 or larger before 2050? It is very hard to use either the Theory of Equally Likely Outcomes or the Frequency Theory to make sense of the assertion. Bayesians, however, assign probabilities to any statement whatsoever, even when no random process is involved. Probability, for a Bayesian, is a way to represent an individuals degree of belief in a statement, given the evidence. Evidential probability, also called Bayesian probability, can be assigned to any statement whatsoever, even when no random process is involved, as a way to represent its subjective plausibility, or the degree to which the statement is supported by the available evidence. On most accounts, evidential probabilities are considered to be degrees of belief, defined in terms of dispositions to gamble at certain odds. The four main evidential interpretations are the classical interpretation, the subjective interpretation, the epistemic or inductive interpretation, and the logical interpretation. Theory: Like other theories, the theory of probability is a representation of probabilistic concepts in formal terms-that is, in terms that can be considered separately from their meaning. These formal terms are manipulated by the rules of mathematics and logic, and any results are then interpreted or translated back into the problem domain. There have been at least two successful attempts to formalize probability, namely the Kolmogorov formulation and the Cox formulation. In Kolmogorovs formulation, sets are interpreted as events and probability itself as a measure on a class of sets. In Coxs theorem, probability is taken as a primitive and the emphasis is on constructing a consistent assignment of probability values to propositions. In both cases, the laws of probability are the same, except for technical details. There are other methods for quantifying uncertainty, such as the Dempster-Shafer theory or possibility theory, but those are essentially different and not compatible with the laws of probability as they are usually understood. Mathematical Treatment: In mathematics, a probability of an event A is represented by a real number in the range from 0 to 1 and written as P(A), p(A) or Pr(A). An impossible event has a probability of 0, and a certain event has a probability of 1. However, the converses are not always true: probability 0 events are not always impossible, nor probability 1 events certain. The opposite or complement of an event A is the event (that is, the event of A not occurring); its probability is given by P(not A) = 1 P(A). As an example, the chance of not rolling a six on a six-sided die is 1 (chance of rolling a six) . If both the events A and B occur on a single performance of an experiment this is called the intersection or joint probability of A and B, denoted as . If two events, A and B are independent then the joint probability is For example: if two coins are flipped the chance of both being heads is If either event A or event B or both events occur on a single performance of an experiment this is called the union of the events A and B denoted as . If two events are mutually exclusive then the probability of either occurring is For example, the chance of rolling a 1 or 2 on a six-sided die is If the events are not mutually exclusive then Conditional probability is the probability of some event A, given the occurrence of some other event B. Conditional probability is written P(A|B), and is read the probability of A, given B. It is defined by If P(B) = 0 then is undefined. Applications: Two major applications of probability theory in everyday life are in risk assessment and in trade on commodity markets. Governments typically apply probabilistic methods in environmental regulation where it is called pathway analysis, often measuring well-being using methods that are stochastic in nature, and choosing projects to undertake based on statistical analyses of their probable effect on the population as a whole. A good example is the effect of the perceived probability of any widespread Middle East conflict on oil prices which have ripple effects in the economy as a whole. An assessment by a commodity trader that a war is more likely vs. less likely sends prices up or down, and signals other traders of that opinion. Accordingly, the probabilities are not assessed independently nor necessarily very rationally. The theory of behavioural finance emerged to describe the effect of such groupthink on pricing, on policy, and on peace and conflict. It can reasonably be said that the discovery of rigorous methods to assess and combine probability assessments has had a profound effect on modern society. Accordingly, it may be of some importance to most citizens to understand how odds and probability assessments are made, and how they contribute to reputations and to decisions, especially in a democracy. Another significant application of probability theory in everyday life is reliability. Many consumer products, such as automobiles and consumer electronics, utilize reliability theory in the design of the product in order to reduce the probability of failure. The probability of failure may be closely associated with the products warranty. Probability Of Winning A Lottery: Everyone knows that the probability of winning the lottery is a pretty big long shot. How long, however, you probably never really thought about. Your actual odds of winning the lottery depend on where you play, but single state lotteries usually have odds of about 18 million to 1 while multiple state lotteries have odds as high as 120 million to 1. If you have ever thought youd win the lottery, youre not alone. About one out of every three people in the United States think that winning the lottery is the only way to become financially secure in their life. This is a frightening statistic when you sit down and consider what the above odds really mean. Its time to take a long hard look at the chances of you winning the lottery. While winning the lottery may be something that you want, to show you your chances well take a look at a number of remote occurrences that you probably wouldnt like to have happen to you and probably dont think will ever happen to you but are still much more likely to happen to you than winning the lottery. How about the classic odds of being struck by lightning? The actual probability of this happening varies from year to year, but as a good estimate, the National Safety Council says between 70 and 120 people a year die in the US by lightning so lets take 100 as our base. With the US population being approximately 265 million people, that means that the chances of being killed by lightning are roughly 2,650,000 to 1. Not very likely. However you are still 6 to 45 times more likely to die from a lightning strike than you would be to win the lottery. Now nobody really wants to die from flesh eating bacteria, and with odds at about 1 million to 1, the chances that you will die that way are pretty slim. Then again, you are 18 to 120 times more likely to die this way than to win the lottery. What are the chances that if youre playing with a group of four that two of you will get a hole-in-one on the exact same hole? At 17 million to 1, theyre better than the chances of you winning the lottery. What about dying from a snake bite or bee sting? It probably isnt a way that you have imagined that you would leave the earth. Youre a whopping 180 to 1,200 times more likely to die from one of these incidents than win the lottery. Thats because the probability of dying from a snake bite or bee sting is about 100,000 to 1. Now I know that you are not a bad person and you dont imagine finding yourself on death row for a crime you committed anytime soon. Still, its a lot more likely that you will be legally executed than win the lottery. In fact, you are 30,000% to 200,000% more likely to die in a legal execution than to win the lottery. If none of the above has convinced you to stop playing the lottery, then Ill bring out my favorite lottery fact. If you drive 10 miles to purchase your lottery ticket, its three to twenty times more likely for you to be killed in a car accident along the way than to win the jackpot. Flipping Of Coin: Coin flipping or coin tossing is the practice of throwing a coin in the air to choose between two alternatives, sometimes to resolve a dispute between two parties. It is a form of sortition which inherently has only two possible and equally likely outcomes. Experimental and theoretical analysis of coin tossing has shown that the outcome is predictable. During coin flipping the coin is tossed into the air such that it rotates end-over-end several times. Either beforehand or when the coin is in the air, an interested party calls heads or tails, indicating which side of the coin that party is choosing. The other party is assigned the opposite side. Depending on custom, the coin may be caught, caught and inverted, or allowed to land on the ground. When the coin comes to rest, the toss is complete and the party who called or was assigned the face-up side is declared the winner. If the outcome is unclear the toss is repeated; for example the coin may, very rarely, land on edge, or fall down a drain. The coin may be any type as long as it has two distinct sides; it need not be a coin as such. Human intuition about conditional probability is often very poor and can give rise to some seemingly surprising observations. For example, if the successive tosses of a coin are recorded as a string of H and T, then for any trial of tosses, it is twice as likely that the triplet TTH will occur before THT than after it. It is three times as likely that THH will precede HHT. Are we likely to be struck by lightning? In the United States, an average of 80 people are killed by lightning each year. Considering being killed by lightning to be our favorable outcome (not such a favorable outcome!), the sample space contains the entire population of the United States (about 250 million). If we assume that all the people in our sample space are equally likely to be killed by lightning (so people who never go outside have the same chance of being killed by lightning as those who stand by flagpoles in large open fields during thunderstorms), the chance of being killed by lightning in the United States is equal to 80/250 million, or a probability of about .000032%. Clearly, you are much more likely to die in a car accident than by being struck by lightning. Probability in Our Lives: A basic understanding of probability makes it possible to understand everything from batting averages to the weather report or your chances of being struck by lightning! Probability is an important topic in mathematics because the probability of certain events happening or not happening can be important to us in the real world. Weather forecasting: Suppose a person wants to go on a picnic this afternoon, and the weather report says that the chance of rain is 70%? Will he ever wonder where that 70% came from? Forecasts like these can be calculated by the people who work for the National Weather Service when they look at all other days in their historical database that have the same weather characteristics (temperature, pressure, humidity, etc.) and determine that on 70% of similar days in the past, it rained. As weve seen, to find basic probability we divide the number of favorable outcomes by the total number of possible outcomes in our sample space. If were looking for the chance it will rain, this will be the number of days in our database that it rained divided by the total number of similar days in our database. If our meteorologist has data for 100 days with similar weather conditions (the sample space and therefore the denominator of our fraction), and on 70 of these days it rained (a favorable outcome), the probability of rain on the next similar day is 70/100 or 70%. Since a 50% probability means that an event is as likely to occur as not, 70%, which is greater than 50%, means that it is more likely to rain than not. But what is the probability that it wont rain? Remember that because the favourable outcomes represent all the possible ways that an event can occur, the sum of the various probabilities must equal 1 or 100%, so 100% 70% = 30%, and the probability that it wont rain is 30%. Bernoulli Trials On Probability: It happens very often in real life that an event may have only two outcomes that matter. For example, either you pass an exam or you do not pass an exam, either you get the job you applied for or you do not get the job, either your flight is delayed or it departs on time, etc. The probability theory abstraction of all such situations is a Bernoulli trial. Bernoulli trial is an experiment with only two possible outcomes that have positive probabilities p and q such that p + q = 1. The outcomes are said to be success and failure, and are commonly denoted as S and F or, say, 1 and 0. For example, when rolling a die, we may be only interested whether 1 shows up, in which case,naturally, P(S) = 1/6 and P(F) = 5/6. If, when rolling two dice, we are only interested whether the sum on two dice is 11, P(S) = 1/18, P(F) = 17/18. The Bernoulli process is a succession of independent Bernoulli trials with the same probability of success. Uses Of Probability In Our Daily Lives: I think we use probability routinely in our daily lives. When you get into a car and drive on public roads, we often assume that we have a low probability of being hit by another car. When you pull out onto a busy street crossing 2 lanes of traffic, you judge the speed of the traffic in those lanes. You assume you have a high probability of judging that speed correctly when you cross those lanes. If you did not make that assumption, you probably would not attempt to cross the lanes for fear of being hit by another car. We assume that we have a low probability of being hit by lightning or a meteor. When you eat with your hands, you assume your probability of getting sick from germs on your hands is low. Or you wouldnt eat with your hands. You could say the same of eating in a restaurant with reference to food you didnt prepare yourself. Within assuming many probabilities, I think wed constantly live in fear of what horrible things might happen to us. Summary of probabilities: Event Probability A not A A or B A and B A given B Other Cases Where Probability Can Be Observed: Youve seen it happen many times-a player in a dice game claims she is due for doubles; strangers discover that they have a mutual acquaintance and think that this must be more than a chance meeting; a friend plays the lottery obsessively or enters online contests with a persistent dream of winning. All these behaviors reflect how people perceive probability in daily life. People who lack an accurate sense of probability are easily drawn in by false claims and pseudoscience, are vulnerable to get-rich-quick schemes, and exhibit many of the behaviors mentioned above. The modeling and measurement of probabilities are fundamentals of mathematics that can be applied to the world around us. Every event, every measurement, every game, every accident, and even the nature of matter itself is understood through probabilistic models, yet few people have a good grasp of the nature of probability. Frequentists talk about probabilities only when dealing with experiments that are random and well-defined. The probability of a random event denotes the relative frequency of occurrence of an experiments outcome, when repeating the experiment. Frequentists consider probability to be the relative frequency in the long run of outcomes.[1] Bayesians, however, assign probabilities to any statement whatsoever, even when no random process is involved. Probability, for a Bayesian, is a way to represent an individuals degree of belief in a statement, or an objective degree of rational belief, given the evidence. Relation to randomness: In a deterministic universe, based on Newtonian concepts, there is no probability if all conditions are known. In the case of a roulette wheel, if the force of the hand and the period of that force are known, then the number on which the ball will stop would be a certainty. Of course, this also assumes knowledge of inertia and friction of the wheel, weight, smoothness and roundness of the ball, variations in hand speed during the turning and so forth. A probabilistic description can thus be more useful than Newtonian mechanics for analyzing the pattern of outcomes of repeated rolls of roulette wheel. Physicists face the same situation in kinetic theory of gases, where the system, while deterministic in principle, is so complex (with the number of molecules typically the order of magnitude of Avogadro constant 6.02 ·1023) that only statistical description of its properties is feasible. A revolutionary discovery of 20th century physics was the random character of all physical processes that occur at sub-atomic scales and are governed by the laws of quantum mechanics. The wave function itself evolves deterministically as long as no observation is made, but, according to the prevailing Copenhagen interpretation, the randomness caused by the wave function collapsing when an observation is made, is fundamental. This means that probability theory is required to describe nature. Others never came to terms with the loss of determinism. Albert Einstein famously remarked in a letter to Max Born: I am convinced that God does not play dice. Although alternative viewpoints exist, such as that of quantum de-coherence being the cause of an apparent random collapse, at present there is a firm consensus among physicists that probability theory is necessary to describe quantum phenomena.

Monday, January 20, 2020

A Human Transporter Protein that Mediates the Final Excretion Step for

Introduction The kidney is an excretory organ that filters wastes from blood and excretes them as urine. Blood plasma filtration occurs at the glomerulus, which is a network of capillaries. Transporters are specialized proteins located in the membranes of the nephron. There are different concentrations of transporters located at various regions of the nephron. For instance, the proximal tubule retains most of the sodium transporters. Some transporters require adenosine triphosphate while others perform passive transport. The method of excretion of toxic organic compounds in mammals is mainly through the kidney and liver. Toxic organic compounds are absorbed by the basolateral membranes and later excreted by brush border membranes that absorb nutrients from the small intestine. These toxic organic compounds are also absorbed by hepatocytes at the sinusoidal membranes and excreted through the bile canaliculi. The objective of this research is to identify the transporter involved with the final step of excretion of toxic organic chemicals. Based on biochemical and physiological studies of the organic compound exporter, the tentative hypothesis proposed is that mammalian orthologues of bacterial multidrug are involved with the excretion of organic compounds. These multidrug transporters include the ?major facilitator superfamily, the small multidrug resistance family, the resistance nodulation cell division family, the ATP binding cassette family, and the multidrug and toxin extrusion (M ATE) family (8?10)?. The MATE family proteins facilitate the coupled export between hydrogen and sodium ions of cationic drugs in bacteria. In this experiment, MATE1 is revealed as the transporter involved with the final... ... locations fit the description of a H+ coupled organic cation transporter. Does hMATE have the correct physiological fingerprint for a toxic organic cation exporter? Yes! Even before they discovered this protein transporter, physiologists had a set of characteristics that this unknown transport protein would display. This protein would be pH sensitive, use H+ as the active step in secondary active transport, and saturable of course. In addition, this protein is found just where it should be, in the apical regions of tubes in the kidney and liver. Since hMATE fits the description, it is a convincing suspect for exporting toxic organic cations. Sources Article: A human transporter protein that mediates the final excretion step for toxic organic cations. By: Masato Otsuka, Takuya Matsumoto, Riyo Morimoto, Shigeo Arioka, Hiroshi Omote, and Yoshinori Moriyama

Sunday, January 12, 2020

Innocent Smoothies

Innocent drink case study analysis: Innocent drinks are a unique business selling 100% natural fruit smoothies. (Innocent drinks) There are many factors that contribute to the company’s successful development so far. Firstly, and most importantly, their unique selling point which is using just fresh fruit in their drinks. This is a major strength to the company as they fit in today’s trend of a healthy eating lifestyle. â€Å"They contain even more antioxidants than the average five a day† (Adams 2007). Moreover Innocent has environmentally friendly packaging; their bottles are clear with simple product information in one colour. Straight away this makes it stand out more than the rest on that shop shelf. â€Å"They were the first company in the world to put drinks on shelves in 100% recycled plastic bottles† (Oracle 2008). However they did not carry out in depth research, they only asked consumers one question: â€Å"Do you think we should give up our jobs to make these smoothies? † (Bains et. al. 2008). No questions related to the product that could help them in the future were asked. Moreover the founders abided by their principles and they only produced their products how they wanted to. This had moved them from a niche market to a nationalised company, now holding more than half of the market share. Furthermore they have met their social responsibilities in many ways such as projects in India, providing food for the homeless and the big knit- providing warmth for the elderly. â€Å"We knitted 20,000 hats to raise ? 10,000 money for Age Concern† (Innocent drinks) Another factor of success to Innocent is their fun and informal business style. Their organisational structure is unique as their staff get bonuses on having children and snowboarding holidays. Even their website is fun-filled excitement; it has its own attractive style it tells you everything about them. Lester (2007) explains â€Å"Their Company’s offices are among the friendliest and relaxed in the world† However the difficulties that company’s like Innocent drinks face are firstly lack of experience and knowledge. Lester (2007) describes â€Å"Its founders had no real experience in the sector. † Moreover raising capital, the founders of Innocent being foolish gave their jobs up straight away without any solid plans. Lester (2007) explains â€Å"They needed to raise money to buy fruit and bottles and get the smoothies made. † However capital problems can be solved by finding ‘Business Angels’. Innocent also found theirs – a wealthy American Maurice Pinto, had the experience and the `money; he was highly impressed by Innocent. â€Å"Maurice decided to invest ? 250,000 in return for 20% stake in the business† (Lester 2007). Furthermore many new businesses underestimate things like how much raw material they will need, this was similar to Innocent. They had only ever made small quantities of their juices but were looking to expand across the nation† (Lester 2007). But using fresh fruits meant that the drinks will be perishable quicker and will have to be sold really quickly. Having too many founders can also be an obstacle to a small business. Innocent had three founders, which meant there were conflicts and every decision had to be discussed and debated befor e reaching a conclusion. This can slow down progress. Innocent have many more business opportunities now that they are a successfully developed business. They have already started to expand their product range in making further products like desserts. They could furthermore develop their product range from ice-creams to maybe even meals, keeping to their principles of healthy eating. Moreover, with the right market research, if these products became successful, they could even open up shops, even restaurants or cafes and possibly start selling online too. These are opportunities because â€Å"By differentiating the products or service the company increase the value of its operators and hence, improves performance† (Bradley 2002 p21). They could further enhance their existing products starting with new packaging, a new style, new combination of colours or even new sizes (king/snack size). Ali (2001 pg 24) suggests firms should â€Å"Keep products fresh by introducing new variants and improved versions†. Using incentives is a good way to get attention, Innocent could offer a free soft toy cow, or a free membership pass to a gym. Innocent use testimonials on their website, they could use famous faces to make these testimonials stand out more. Ali (2001 p11) also explains that a business should â€Å"Look at the various aspects of their business that customers use to form a view of you† Lastly Innocent could sponsor big charity events and music shows, this way they are being ethically responsible and they raise awareness about their products. All of these suggestions would contribute to reducing the risk of business failure for Innocent drinks in the future. Innocent is a fast growing business and one of the most successful. However Page, Ralph and Jones (1989 p 1-55) explain fast growth in a short period of time is a threat. Having to produce on a large scale and making deliveries on time can be difficult. Forecasting demand and market growth is essential; firms almost fail predicting this incorrectly. A fast growing business like Innocent, need to keep track of forecasts as accurately as they can, or they can lose their reputation and money. For example, â€Å"Firms need skill in measuring and forecasting the size, growth, and profit potential† (Kotler 1994 p 245). Also Innocent will have to be aware of changing trends and tastes in their market, drastic changes in the market can affect Innocent. However there are also external threats to Innocent like competition (Myroslaw 1987 p 45). They need to keep a constant watch on competitors to make comparisons with their own business. Moreover change in economic conditions effect firms, currently the economy is suffering a recession; (www. news. bbc. co. uk) during these times it would be best to lower prices. Even more technology changes can be threatening to the position of a firm, Innocent might need to update their current technology and re-train their employees. Finally meeting their liabilities, avoiding bad debts and cash flow problems will contribute to a firm’s success. In conclusion Innocent drinks is proven to be a surprisingly successful business even after all the struggles, they came through as a strong and honest business. However they now need to be extra careful because they have reached a high level of success, and the higher you are the harder it becomes to maintain that position. Word count: 1,062 Bibliography: Anthony S. Page, Ralph C. Jones (1989) ‘Business Growth – How to Achieve and Sustain It’, Leadership & Organization Development Journal, 10(2) p 1-55. Ali, M. (2001) Marketing Effectively, Hampton, Dorling Kindersley. Baines, P. Fill, C. and Page, K. (2008) Marketing. Oxford: Oxford University Press. Bradley, F. (2002) International Marketing Strategy, Dublin, Pearson Education. Kotler, P. (1994) Marketing Management, USA, Prentice Hall. Myroslaw J. (1987) ‘customer service competition business to business and industrial market’ Journal of Business & Industrial Marketing, 2(4) p45-52. ttp://www. innocentdrinks. co. uk/us/? Page=our_story Accessed 21/11/08 http://www. innocentdrinks. co. uk/bored/ Accessed 21/11/08 http://money. aol. co. uk/small-business/innocent-drinks-coming-to-fruition/article/20070814091309990004 Accessed 19/11/08 http://www. oracle. com/customers/snapshots/innocent-drinks-demantra-snapshot. pdf Accessed 21/11/08 http://www. drinks-business-review. com/art icle_feature. asp? guid=55937F47-8134-4E4F-A9A4-881AE440062F Accessed 21/11/08 http://news. bbc. co. uk/1/hi/magazine/7686531. stm Accessed 01/12/08